Franklin & Marshall College Franklin & Marshall College

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Courses Offered

A list of regularly offered courses follows. Please note the key for the following abbreviations: (A) Arts; (H) Humanities; (S) Social Sciences; (N) Natural Sciences with Laboratory; (LS) Language Studies requirement; (NSP) Natural Science in Perspective; (NW) Non-Western Cultures requirement.

111. General Chemistry I: The Structure and Composition of Matter. (N)

Designed both as a background for further courses in chemistry and as a terminal course for interested non-science students. Atomic structure, chemical bonding, molecular structure, intermolecular forces and the structure of matter in bulk. Relationship between properties and structure stressed throughout. Laboratory work deals with the separation and identification of substances. Offered every Fall.    
Brandt, Hess, Hofmann, Phillips-Piro, Plass, Pruet, Seiders

112. General Chemistry II: Chemical Reactions. (N)

The principles underlying chemical transformations: stoichiometry; rates of reaction; equilibrium, metathetical, acid-base and oxidation-reduction reactions. Laboratory work dealing with the separation and identification of substances. Prerequisite: CHM 111. Offered every Spring.            
Brandt, Brewer, Hess, Morford, Phillips-Piro, Plass, Pruet, Seiders

211. Organic Chemistry I: Structure, Rates and Mechanisms. (N)

Structure and bonding principles associated with carbon compounds, fundamental reaction types with emphasis upon mechanisms. Structure determination based on theory and application of infrared spectroscopy, proton and carbon-13 nuclear magnetic resonance spectroscopy and mass spectrometry. Laboratory work required includes separation, identification and synthesis of compounds. Prerequisite: CHM 112. Offered every Fall.    
Fenlon, Leber, Pruet, Thomsen, Van Arman

212. Organic Chemistry II: Reactions of Carbon Compounds. (N)

Reactions of carbon compounds as a function of their molecular structures with emphasis on mechanisms and the use of these reactions in synthesis of carbon compounds. Laboratory work involving analysis and synthesis of various compounds. Prerequisite: CHM 211. Offered every Spring.    
Fenlon, Leber, Thomsen, Van Arman

221. Chemical Analysis. (N)

Fundamental principles of chemical analysis including solution equilibria, acid-base theory, complexation reactions and electrochemistry. Sampling and experimental design; interpretation and analysis of experimental results. Laboratory work includes introduction to common instrumental methods with applications drawn from fields such as biochemistry, environmental chemistry, forensic chemistry and pharmaceutical analysis. Prerequisite: CHM 112. Offered every Fall.    
Hess, Morford

222. Inorganic Chemistry: Structure and Stability. (N)

Periodic relationships and acid-base concepts. Structure, bonding, reactions, and stability of main group and transition metal compounds, including use of group theory. Laboratory work involving the synthesis and characterization of inorganic compounds. Prerequisites: CHM 112. Offered every Spring.    

321. Thermodynamics and Kinetics. (N)

Kinetic molecular theory of gases. Properties of real and ideal gases. Kinetics and mechanisms of reactions; theories of reaction rate. The laws of thermodynamics, spontaneity and equilibrium, systems of variable composition, phase equilibria, phase diagrams. Ideal solutions and colligative properties. Laboratory work required. Prerequisites: CHM 112, MAT 110, PHY 111 (or PHY111 may be a corequisite with permission of instructor). Offered every Fall.   

322. Structure and Bonding. (N)

An introduction to quantum chemistry and spectroscopy of atoms and molecules, including bonding theories. Applications of molecular modeling and group theory to atomic and molecular structure and spectroscopy. Prerequisites: CHM 211 or CHM 222; MAT 110, PHY 112. Offered every Spring.

323. Medicinal Chemistry. (half-course)

The mechanism of action of several classes of drugs. The discovery (e.g., natural products, rational design, combinatorial chemistry), structure-activity relationships, and synthesis of drugs will be covered. The role of the FDA, ethical issues, and economic pressures in relation to drug pricing, approval, and manufacture will be discussed (no lab). Prerequisite: CHM212.     

351. Introductory Biochemistry. (N)

This course will examine how chemical principles apply to life-sustaining processes in a variety of biological systems. Students will gain an understanding of protein and nucleic acid structure, how these molecules are synthesized by the cell, and the reactions they perform or undergo. We will also discuss the chemical transformations afforded by organic and inorganic small molecule cofactors utilized by biological molecules in the cell. . Laboratory work will cover a variety of biomechanical techniques including protein expression, purification, kinetics, and structure analysis. Prerequisite: CHM 212. Offered every Fall.     

370 – 379. Topics in Chemistry.

Study of specialized areas of modern chemistry.  Staff

390. Directed Studies of Chemical Problems.

Directed study of a one-semester project. Permission of instructor required. A student may not use this course to satisfy a major requirement in addition to CHM 490.  Staff

 451. Advanced Biochemistry.

How do interactions among atoms result in a living organism? How does molecular organization lead to biological organization? This course will focus on the atomic-level detail of biological interactions. Students will engage with the primary scientific literature, culminating in a research proposal addressing a contemporary research question. The folding and three-dimensional structure of biological macromolecules, molecular recognition, affinity and selectivity of binding, catalysis by enzymes and biomimetic design. The capabilities and limitations of modern experimental tools will be a theme throughout. Prerequisites: CHM 321, CHM 212 and either CHM 351, CHM371 or BIO 334. Open to senior chemistry majors and senior BMB majors. Offered every Spring.

473. Materials Chemistry.

Relationships between the properties of technological devices and their component materials in a chemical context. Experimental characterization of device and material properties. Coursework will require reading the primary literature. Prerequisites: CHM 212, CHM222, CHM 321, CHM 322 (or CHM 322 may be a co-requisite with permission of instructor). Open only to senior chemistry majors.    

490. Independent Study.

Independent study extending over two semesters. Course credit earned each semester. Permission of chairperson required.  Staff