B.S. Biology    Allegheny College

Ph.D. Molecular Genetics   Penn State College of Medicine

Postdoctoral Fellow   National Institute on Aging, National Insitiutes of Health


Baptiste, B.A., K.D. Jacob, and K.A. Eckert (2015).  Genetic Evidence That Both dNTP-Stabilized and Strand Slippage Mechanisms May Dictate DNA Polymerase Errors Within Mononucleotide Microsatellites.  DNA Repair  doi:10.1016/j.dnarep.2015.02.016

Jacob, K.D., Noren Hooten, N., Tadokoro, T., Lohani, A., Barnes, J., and M.K. Evans.  Alzheimer’s Disease Associated Polymorphisms in Human OGG1 Alter Catalytic Activity and Sensitize Cells to DNA Damage (2013).  Free Radical Biology & Medicine 63:115-125

Jacob, K.D., N. Noren Hooten, A.R. Trzeciak, and M.K. Evans (2013).  Markers of Oxidant Stress that are Clinically Relevant in Aging and Disease. Mechanisms of Aging and Development 134(3-4):139-57

Guruprasad, A, Walsh, E., Jacob, K.D., Krasilnikova, M., Eckert, K.A., Chiaromonte, K., and K. D. Makova (2012).  Distinct microsatellites in the human genome mutational behaviors distinguish simple tandem repeats from microsatellites in the human genome. Genome Biology and Evolution Jan;5(3):606-20

Noren Hooten, N., Fitzpatrick, M, Kompaniez, K., Jacob, K.D., Moore, B., Nagle, J., Barnes, J., Lohani, A., and M.K. Evans (2012).  NEIL1 and PARP-1 interact to coordinate DNA repair.  Aging 4(10):674-85.

Trzeciak, A.R.,  J.G. Mohanty, K.D. Jacob, J. Barnes, A. Lohani, N. Ejiogu, A.B. Zonderman, J. Rifkind, and M.K. Evans (2012). Oxidative Damage to DNA and Single Strand Break Repair Capacity: Relationship to other Measures of Oxidative Stress in a Population Cohort.  Mutation Research 736(1-2):93-103

Jacob, K.D. and K.A. Eckert (2007).  Escherichia coli DNA Polymerase IV Contributes to Spontaneous Mutagenesis at Coding Sequences but not Microsatellite Alleles.  Mutation Research 619(1-2):93-103