Fall 2020 Office Hours:
Work in my lab involves the interface of synthetic organic chemistry and medicinal chemistry. I am driven to discover and develop new reactions that will not only enable or shorten synthesis of small heterocyclic compounds, but also have a broader impact on the study of biological systems and in drug discovery.
American Chemical Society Petroleum Research Fund Undergraduate New Investigator Grant
Prior to F&M
HHMI Postdoctoral Fellowship of the Damon Runyon Cancer Research Foundation National Science Foundation Graduate Fellowship
MIT Presidential Fellowship
MIT Graduate Woman of Excellence Award
MIT Spot Award for Service to the School of Science
Beckman Foundation Scholar
National Merit Scholar
Howard Hughes Medical Institute Scholarship
Publications & Patents
F&M Undergraduate co-authors are in bold and corresponding authors are indicated with an asterisk. Equal author contributions are indicated by †
Tasker, S. Z., Cowfer, A. E.; Hergenrother, P. J.* Preparation of Structurally Diverse Compounds from the Natural Product Lycorine. Org. Lett. 2018, 20, 5894-5898.
Gates, Z. P.; Viogradov, A. A.; Quartararo, A. J.; Bandyopadhyay, A.; Choo, Z.-N.; Evans, E. D.; Halloran, K. H.; Mijalis, A. J.; Mong, S. K.; Simon, M. D.; Standley, E. A.; Styduhar, E. D.; Tasker, S. Z.; Touti, F.; Weber, J. M.; Wilson, J. L.; Jamison, T. F.;* Pentelute, B. L*. ‘Xenoprotein’ Engineering via Synthetic Libraries. Proc. Natl. Acad. Sci. 2018, 115, E5298-E5306.
Hergenrother, P. J.;* Richter, M.; Riley, A.; Drown, B.; Chavez, M.; Tasker, S.; Garcia, A. Small-Molecules Active Against Gram-Negative Bacteria. International Patent WO2017/156519A1, Sept. 2017.
Tasker, S. Z.; Hergenrother, P. J.* Taming Reactive Benzynes. Nature Chem. 2017, 9, 504–506 (News & Views)
Tasker, S. Z.; Jamison, T. F.* Highly Regioselective Indoline Synthesis under Nickel/ Photoredox Dual Catalysis. J. Am. Chem. Soc. 2015, 137, 9531–9534.
Standley, E. A.;† Tasker, S. Z.;†;Jensen, K. L.; Jamison, T. F.* Nickel Catalysis: Synergy between Method Development and Total Synthesis. Acc. Chem. Res. 2015, 48, 1503–1518.
Standley, E. A.;† Tasker, S. Z.;† Jamison, T. F.* Bis(1,5-cyclooctadiene)nickel(0). e-EROS Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons, Ltd. Published online Sept. 20, 2015.
Tasker, S. Z.;† Standley, E. A.;† Jamison, T. F.* Recent Advances in Homogeneous Nickel Catalysis. Nature 2014, 509, 299–309.
Tasker, S. Z.; Gutierrez, A. C.; Jamison, T. F.* Nickel-Catalyzed Mizoroki–Heck Reaction of Aryl Sulfonates and Chlorides with Electronically Unbiased Terminal Olefins: High Selectivity for Branched Products. Angew. Chem., Int. Ed. 2013, 53, 1858–1861.
Tasker, S. Z.; Bosscher, M. A.; Shandro, C. A.; Lanni, E. L.; Ryu, K. A.; Snapper, G. S.; Utter, J. M.; Ellsworth, B. A.; Anderson, C. E.* Preparation of N-Alkyl 2-Pyridones via a Lithium Iodide Promoted O- to N-Alkyl Migration: Scope and Mechanism. J. Org. Chem. 2012, 77, 8220–8230.
Tasker, S. Z.; Brandsen, B. M.; Ryu, K. A.; Snapper, G. S.; Staples, R. J.; DeKock, R. L.;* Anderson, C. E.* Synthesis of a New Class of β-Iodo N-Alkenyl 2-Pyridones. Org. Lett. 2011, 13, 6224–6227.
CHM211: Organic Chemistry I, Lecture & Lab
CHM212: Organic Chemistry II, Lecture & Lab
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